22 Open NAICS 541714 Government Contracts
Research and Development in Biotechnology (except Nanobiotechnology)
22 open solicitations are currently posted under NAICS 541714 (Research and Development in Biotechnology (except Nanobiotechnology)). Over the past 12 months, agencies posted 68 solicitations, with DEPT OF DEFENSE, HEALTH AND HUMAN SERVICES, DEPARTMENT OF, VETERANS AFFAIRS, DEPARTMENT OF among the top buyers. Data is refreshed daily from SAM.gov.
Top Buying Agencies (Last 12 Months)
- DEPT OF DEFENSE44 solicitations
- HEALTH AND HUMAN SERVICES, DEPARTMENT OF44 solicitations
- VETERANS AFFAIRS, DEPARTMENT OF8 solicitations
- AGRICULTURE, DEPARTMENT OF7 solicitations
- NATIONAL AERONAUTICS AND SPACE ADMINISTRATION6 solicitations
Top Award Winners (Last 12 Months)
- ENGINEERING BIOLOGY RESEARCH CONSORTIUM1 awards · $1.2M
- Flosonics Medical LLC1 awards · $99.7M
- ILLUMINA, INC.1 awards · $273K
- NATIONAL COLLEGIATE INVENTORS & INNOVATORS ALLIANCE, INC.1 awards · $1.4M
- TWIST BIOSCIENCE CORPORATION1 awards · $47K
Open Solicitations
See all →- Low-Pass Sequencing of Cotton Accessions - College Station TX
AGRICULTURE, DEPARTMENT OFNAICS 541714Due Aug 26, 2026
• The Department of Agriculture requests quotes for low-pass sequencing of cotton accessions. • Acquisition shall meet specific technical and quality standards as determined by the USDA. • The solicitation is an unrestricted requirement for small businesses and large contractors alike.
- Yeast Two-Hybrid (Y2H) Screening Service
AGRICULTURE, DEPARTMENT OFNAICS 541714Due Aug 28, 2026
• Yeast Two-Hybrid (Y2H) screening service is required for the Robert W. Holley Center for Agriculture and Health located at Cornell University. • The Y2H screening service must adhere to the standards outlined in the Department of Health and Human Services Code of Federal Regulation, specifically 21 CFR Part 51. • The scope of the work includes the use of reagents, kits, and instrumentation as described by Qiagen or similar products for research purposes at Cornell University's Robert W. Holley Center for Agriculture and Health. • Responses should address both the prime contractor's need to purchase high-quality Y2H screening services from a qualified supplier.
- Bridge Contract - Disease Surveillance and Research Support
DEPT OF DEFENSENAICS 541714Due Sep 4, 2026
• The Defense Health Agency Contracting Activity (DHACA) intends to negotiate a sole source 12-month bridge contract on a fixed award basis. • As a sole responsible source, DHACA will partner with THE HENRY M. JACKSON FOUNDATION for the Advancement of Military Medicine, Inc. (the Foundation). • The service to be provided by the Foundation relates to surveillance or research services in assessing infectious diseases on Africa, including Ethiopia, Kenya, Nigeria, Somalia, Tanzania, Uganda. • Responses are due June 15, 2026.
- Hypoxia Chamber Services
NATIONAL AERONAUTICS AND SPACE ADMINISTRATIONNAICS 541714Due Sep 10, 2026
• The US Army Corps of Engineers requires dredging services at McAlpine Locks and Dam on the Ohio River near Louisville, Kentucky to maintain a navigable channel depth of 9 feet. • This is an unrestricted, full and open competition under NAICS 237990 (Other Heavy and Civil Engineering Construction) for vessel-based maintenance and repair work. • The scope includes infrastructure, personnel, training, materials, foods, supplies, and operational support necessary for the objective; offers are due July 30, 2026.
- Hypobaric Chamber Pilot Studies
NATIONAL AERONAUTICS AND SPACE ADMINISTRATIONNAICS 541714Due Sep 10, 2026
• This RFQ requires pilot chamber testing facilities capable of performing hypobaric Decompression Sickness (DCS) studies at the McAlpine Locks and Dam on the Ohio River near Louisville, Kentucky. • The NAICS code for the service is 541714, with a size standard of fewer than 100 employees, as per Attachment A - Statement of Work. • Offers must specify that they are multiple award contracting (MAC) contract award notifications, as stated in FAR 52.212-1, Instructions to Offerors-Congressioneered Commercial Products and Services.
- Biological Technologies
DEPT OF DEFENSENAICS 541714Due Sep 30, 2026
• DARPA seeks proposals for research leveraging biological properties to enhance national security. • Open competition with no explicit eligibility set-aside. • Proposals should focus on innovative applications rather than incremental advancements. • No deadline information provided in the solicitation text.
- TECHNOLOGY LICENSING OPPORTUNITY: Platform to Accelerate Discovery of Tailored Industrial Enzymes (PAD-TIE)
ENERGY, DEPARTMENT OFNAICS 541714Due Oct 1, 2026
• PAD-TIE is aPAD-TIE platform designed for simultaneous screening of tens of thousands of enzyme variants with high-throughput efficiencies. • The system evaluates enzyme efficiency, stability, and production potential in industrially relevant conditions using validated lab-scale bioreactors. • Evaluating enzyme variants accelerates discovery by providing insights into viability without requiring individual testing under controlled conditions. • Responses are due June 15, 2026.
- Protein ENGineering (PENG)
DEPT OF DEFENSENAICS 541714Due Oct 19, 2026
• The Protein ENGINEering program aims to transition proteome engineering from isolated tools into a universal, software-defined discipline. • Performers will develop and integrate novel splicing, ligation, and co-translational techniques to modulate endogenous proteins within complex biological architectures. • The platform will include modular targeting, generalizable effector chemistries, and multiplexed control systems for precise editing. • Validation goals include integrating proof-of-concept at the tissue level (high-fidelity cellular models) with subsequent high-fidelity validation in biological systems.
- Protein ENGineering (PENG)
DEPT OF DEFENSENAICS 541714Due Oct 19, 2026
• The DARPA Protein Engineering (PENG) program seeks multiple, splicing-based technologies for editing endogenous proteins in complex biological architectures. • The PENG platform will utilize modular targeting, generalizable effector chemistries, and multiplexed control systems to integrate novel techniques. • High-fidelity cellular models such as organoids will be used to validate the integration of the integrated platform at a tissue level.
- NAWCWD Broad Agency Announcement
DEPT OF DEFENSENAICS 541714Due Oct 30, 2026
• The Naval Air Warfare Center Weapons Division requires innovative technical solutions without issuing a formal RFP. • There are no set-aside or small business program implications specified. • Proposals must address both technical feasibility and cost considerations. • Responses are due based on an undisclosed timeframe, as NAWCWD reserves the right to fund any proposals selected.
- Non-Optical Methods for High Speed Protein Control
DEPT OF DEFENSENAICS 541714Due Dec 8, 2026
• DARPA BTO aims to procure innovative solutions for post-competitive ERIS Marketplace. • Requires development of new protein domains for real-time cellular control. • Must be non-optogenetic and robust, suitable for massless information transfer across a cell membrane. • No specific competition or set-aside program noted in the description.
- TECHNOLOGY LICENSING OPPORTUNITY: DC Recruiter
ENERGY, DEPARTMENT OFNAICS 541714Due Dec 16, 2026
• DC Recruiter from Los Alamos National Laboratory offers a broad-spectrum immune enhancer using a self-assembling peptide nanofiber to activate dendritic cells for multi-pathogen infection prevention. • Competition is unrestricted and open to all businesses under NAICS 51 (Professional, Scientific, and Technical Services). • Key technical requirement includes the use of a specific peptide that can bind to dendritic cells to enhance immune surveillance.
- TECHNOLOGY LICENSING OPPORTUNITY: NanoFET
ENERGY, DEPARTMENT OFNAICS 541714Due Dec 18, 2026
• Los Alamos National Laboratory seeks a NanoFiber Engineered Therapeutics Platform (NanoFET) for the development of next-generation immunotherapies. • Limited to small businesses under NAICS code 541900 (Drug Manufacturing). • The platform must merge self-assembling peptide nanofibers with interchangeable nanobody and peptide components, facilitating rapid customization for various targets.
- TECHNOLOGY LICENSING OPPORTUNITY: Protein-Based Rare Earth Recovery via Condensation
ENERGY, DEPARTMENT OFNAICS 541714Due Dec 23, 2026
• Los Alamos National Laboratory seeks a provider for the development and validation of a protein-based system for rare earth element (REE) recovery from complex liquid mixtures. • This acquisition is not set aside for any specific eligibility program. • Technical details involve modifying Lanmodulin to bind rare earth elements in solution, forming condensates that can be separated and concentrated using various methods such as centrifugation, filtration, and sedimentation. • No specific deadline is provided in the given description.
- Non-Optical Methods for High Speed Protein Control
DEPT OF DEFENSENAICS 541714Due Dec 31, 2026
Here are 3-4 bullet points based on the provided text: • DARPA is soliciting innovative solutions under Amendment 1 to DARPA-SN-26-89, specifically addressing real-time cellular control with post-competitive awardable post-optical protein domains. • The ERIS Marketplace (Evaluating Research Industrial Strategy) will provide a platform for discovering and selecting suitable solutions from active "shopping" by DARPA BTO. • This effort aims to develop a new class of non-optogenetic, switchable protein domains with massless information transfer capabilities across cell membranes for real-time cellular control. • Deadline for responses is unclear, but the period of performance might be influenced by existing synthetic biology platforms.
Recently Awarded (Last 90 Days)
- Chromosome Conformation and Whole Genome Sequencing - KINGSTON RI
AGRICULTURE, DEPARTMENT OF→ DNA LINK USA, INC$12K
- RNCP PORTFOLIO-WIDE DOSIMETRY VERIFICATION SERVICES
HEALTH AND HUMAN SERVICES, DEPARTMENT OF→ UNIVERSITY OF MARYLAND, BALTIMORE$552K
- Bovine IFN Lambda Fc Fusion
AGRICULTURE, DEPARTMENT OF→ GENSCRIPT USA INC$22K
- AN11--MRI Scanning and Image Analysis
VETERANS AFFAIRS, DEPARTMENT OF→ UNIVERSITY OF WASHINGTON$638K
- Methylome End to End Samples Processing Services
VETERANS AFFAIRS, DEPARTMENT OF→ TWIST BIOSCIENCE CORPORATION$47K
- Biosecurity Working Group Generative Optogenetics
DEPT OF DEFENSE→ ENGINEERING BIOLOGY RESEARCH CONSORTIUM$1.2M
- Independent Commercialization Generative Optogenetics
DEPT OF DEFENSE→ NATIONAL COLLEGIATE INVENTORS & INNOVATORS ALLIANCE, INC.$1.4M
- AN13--Histological analysis of H9-scNSC in NHP -WO/WD, BONLY POP 6/1/2026 - 5/31/2027
VETERANS AFFAIRS, DEPARTMENT OF→ VIRSCIO, INC$186K
- Biomedical Advanced Research and Development Authority (BARDA) Broad Agency Announcement (BAA)
HEALTH AND HUMAN SERVICES, DEPARTMENT OF→ Flosonics Medical LLC$99.7M
- Illumina Urinary Pathogen Identification (ID)/Antimicrobial Resistance (AMR) Enrichment Kit (UPIP), (1) Respiratory Pathogen ID/AMR Enrichment Kit Set A,
DEPT OF DEFENSE→ ILLUMINA, INC.$273K
Frequently Asked Questions
What professional services contracts does the federal government award (NAICS 54)?
NAICS sector 54 (Professional, Scientific, and Technical Services) is one of the largest federal contracting sectors, covering IT consulting, engineering, R&D, management consulting, architecture, legal services, and accounting. Major buyers include DoD, DHS, VA, and civilian agencies across all categories.
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Federal contracting opportunities are posted on SAM.gov (System for Award Management). You can search by keyword, NAICS code, set-aside type, agency, and response deadline. FedOps aggregates and enriches SAM.gov data daily so you can filter and track opportunities in one place.
What is a set-aside in federal contracting?
A set-aside is a procurement reserved for a specific category of small business. Common set-asides include SDVOSB (Service-Disabled Veteran-Owned), 8(a), WOSB (Women-Owned), HUBZone, and Small Business. Only businesses that meet the eligibility requirements can bid on a set-aside contract.
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